familial hemophagocytic lymphohistiocytosis

familial hemophagocytic lymphohistiocytosis
an autosomal recessive, genetically heterogeneous type of hemophagocytic lymphohistiocytosis; it is characterized by anemia, granulocytopenia, thrombocytopenia, intense phagocytosis of red blood cells, diffuse proliferation of histiocytes of various organs, and enlargement of the liver, spleen, and lymph nodes; it is usually rapidly fatal if untreated.

Medical dictionary. 2011.

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