lipofuscin

lipofuscin
Brown pigment granules representing lipid-containing residues of lysosomal digestion and considered one of the aging or “wear and tear” pigments; found in liver, kidney, heart muscle, adrenal, and ganglion cells.

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li·po·fus·cin .lip-ə-'fəs-ən, .līp-ō-, -'fyü-sən n a brownish lipochrome found esp. in tissue (as of the heart) of the aged

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n.
a brownish pigment staining with certain fat stains. It is most common in the cells of heart muscle, nerves, and liver and is normally contained within the lysosome.

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lipo·fus·cin (lip″o-fuґsin) 1. a yellow to brown, granular, iron-negative lipid pigment found particularly in muscle, heart, liver, and nerve cells undergoing slow, regressive change and accumulating in lysosomes with age, being the product of oxidation and polymerization of the membrane lipids of autophagocytosed organelles. 2. lipochrome.

Medical dictionary. 2011.

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Look at other dictionaries:

  • lipofuscin — [lip΄ō fus′in, lī΄pōfus′in] n. any of a group of fatty pigments that are found in various body cells and are associated with aging …   English World dictionary

  • Lipofuscin — Micrograph showing lipofuscin in a liver biopsy with ground glass hepatocytes. H E stain. Lipofuscin is the name given to finely granular yellow brown pigment granules[1] …   Wikipedia

  • Lipofuscin — Lipofuszin, auch Lipofuscin, ist ein gelb braunes oxidiertes quervernetztes Aggregat, bestehend aus oxidierten Protein (30–58 %) und Lipidclustern (19–51 %), das sich besonders in Herzmuskel , Leber und Nervenzellen mit der Zeit akkumuliert.[1]… …   Deutsch Wikipedia

  • Lipofuscin — Li|po|fus|cin [↑ Lip lat. fuscus = dunkelbraun, schwärzlich; ↑ in (3)], das; s, e: lipidhaltige, braune Abbau oder Abnutzungspigmente aus Lysosomen, die sich mit zunehmendem Lebensalter vermehrt in Zellen von Herz, Leber u. Nerven ablagern. * * * …   Universal-Lexikon

  • lipofuscin — lipofuscinas statusas T sritis chemija apibrėžtis Geltonas pigmentas, kuris kaupiasi senstančio žmogaus audiniuose. atitikmenys: angl. age pigment; lipofuscin rus. липофусцин …   Chemijos terminų aiškinamasis žodynas

  • lipofuscin — Brown pigment characteristic of ageing. Found in lysosomes and is the product of peroxidation of unsaturated fatty acids and symptomatic, perhaps, of membrane damage rather than being deleterious in its own right …   Dictionary of molecular biology

  • lipofuscin — /lip euh fus in, luy peuh /, n. Biochem. any of several brown pigments similar to melanin that accumulate in animal cells with age and are products of oxidation of lipids and lipoproteins. [1920 25; < G, equiv. to lipo LIPO 1 + L fusc(us) dark,… …   Universalium

  • lipofuscin — noun Any of a family of pigmented lipid granules that accumulates in several body tissues …   Wiktionary

  • lipofuscin — li·po·fus·cin …   English syllables

  • lipofuscin — n. a brownish pigment staining with certain fat stains. It is most common in the cells of heart muscle, nerves, and liver and is normally contained within the lysosomes …   The new mediacal dictionary

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