leucine

leucine
2-Amino-4-methylvaleric acid; the l-isomer is one of the amino acid s found in proteins; a nutritionally essential amino acid.
- l. aminopeptidase aminopeptidase (cytosol).
- l. dehydrogenase an enzyme that catalyzes the reaction of l-l., water, and NAD+ to produce NADH, ammonia, and 4-methyl-2-oxopentanoate; used in the treatment of certain tumors.
- l. zipper a structural motif found in a number of proteins ( e.g., some of the DNA-binding regulatory proteins) in which leucyl residues align along one edge of the helix and can interdigitate with a similar structure on another protein molecule. [Zipper, orig. a trademark for a fastening device with two rows of interlocking teeth]

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leu·cine 'lü-.sēn n a white crystalline essential amino acid C6H13NO2 obtained by the hydrolysis of most dietary proteins abbr. Leu

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n.

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leu·cine (Leu) (L) (looґsēn) [Gr. leukos white] an essential amino acid, 2-amino-4-methylpentanoic acid, necessary for optimal growth in infants and for nitrogen equilibrium in human adults. It is obtained by the digestion or hydrolytic cleavage of protein. See also table at amino acid. [USP] a preparation of leucine used as a dietary supplement.

Medical dictionary. 2011.

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Look at other dictionaries:

  • Leucine — L ou S(+) leucine D ou R( ) leucine Général …   Wikipédia en Français

  • leucine — [ løsin ] n. f. • 1832; de leuc(o) et ine ♦ Biochim. Acide aminé essentiel, l un des vingt constituants des protéines. ⇒ isoleucine. ● leucine nom féminin Aminoacide dont l antipode lévogyre, la L leucine, est un constituant essentiel des… …   Encyclopédie Universelle

  • Leucine — Leu cine (l[=oo] s[=e]n), Leucin Leu cin(l[=u] s[i^]n), n. [Gr. leyko s white.] (Physiol. Chem.) a naturally occurring alpha amino acid ({(CH3)2CH.CH2.CH(NH2) COOH}), one of the building units of almost all proteins of living organisms, both… …   The Collaborative International Dictionary of English

  • leucine — [lo͞o′sēn΄, lo͞o′sin] n. [< Gr leukos, white (see LIGHT1) + INE3] an essential amino acid, (CH3) 2CHCH2CH(NH2)COOH, produced by the hydrolysis of proteins by pancreatic enzymes during digestion and by the putrefaction of nitrogenous organic… …   English World dictionary

  • Leucine — NatOrganicBox name= ( S ) 2 amino 4 methyl pentanoic acid PubChem=6106 CAS=61 90 5 SMILES=CC(C)C [C@H] (N)C(O)=O C=6 |H=13 |N=1 |O=2 mass=131.18 g/molLeucine (abbreviated as Leu or L) [cite web | author=IUPAC IUBMB Joint Commission on Biochemical …   Wikipedia

  • Leucine — Als Leucine fasst man zunächst die vier isomeren Aminosäuren Leucin, Isoleucin, tert Leucin und Norleucin zusammen. Im Vergleich mit den vier Butanolen kann man sie als butylsubstituierte Glycine auffassen; damit sind alle vier Varianten… …   Deutsch Wikipedia

  • leucine — leucinas statusas T sritis chemija formulė (CH₃)₂CHCH₂CH(NH₂)COOH santrumpa( os) Leu, L atitikmenys: angl. leucine rus. лейцин ryšiai: sinonimas – 2 amino 4 metilpentano rūgštis …   Chemijos terminų aiškinamasis žodynas

  • Leucine-2-alanine enkephalin — is a synthetic delta selective opioid peptide with analgesic properties. Treatment with dadle results in transient depression of mean arterial blood pressure and heart rate [http://cancerweb.ncl.ac.uk/cgi bin/omd?enkephalin,+leucine 2 alanine]… …   Wikipedia

  • Leucine-responsive protein — Leucine responsive protein, or Lrp, is a global regulator protein, meaning that it regulates the biosynthesis of leucine, as well as the other branched chain amino acids, valine and isoleucine. In bacteria, it is encoded by the lrp gene.Lrp… …   Wikipedia

  • leucine aminopeptidase — n an aminopeptidase that cleaves terminal amino acid residues and esp. leucine from protein chains, is found in all bodily tissues, and is increased in the serum in some conditions or diseases (as pancreatic carcinoma) * * * (LAP) leu·cine… …   Medical dictionary

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