kynurenine

kynurenine
A product of the metabolism of l-tryptophan, excreted in the urine in small amounts; elevated in cases of vitamin B6 deficiency.
- k. 3-hydroxylase SYN: k. 3-monooxygenase.
- k. 3-monooxygenase an enzyme catalyzing addition of a hydroxyl group to l-k., with the aid of NADPH and O2, producing 3-hydroxy-l-k., NADP+, and water; a step in the catabolism of l-tryptophan. SYN: k. 3-hydroxylase.

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kyn·uren·ine .kīn-yu̇-'ren-.ēn, .kin-, -'yu̇-rən- n an amino acid C10H12N4O3 occurring in the urine of various animals as one of the normal products of tryptophan metabolism

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kyn·ure·nine (kin-uґrə-nēn″) [Gr. kyōn dog + L. ren kidney] an aromatic amino acid, first isolated from dog urine; it is formed as an intermediate in the metabolism of tryptophan.

Medical dictionary. 2011.

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  • Kynurenine — Général Nom IUPAC 2 amino 4 (2 aminophenyl) 4 oxo butanoic acid …   Wikipédia en Français

  • Kynurenine — Chembox new ImageFile=Kynurenine.svg ImageSize= IUPACName=2 amino 4 (2 aminophenyl) 4 oxo butanoic acid OtherNames= Section1= Chembox Identifiers CASNo=343 65 7 PubChem=846 SMILES=C1=CC=C(C(=C1)C(=O)CC(C(=O)O)N)N MeSHName=Kynurenine Section2=… …   Wikipedia

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  • Kynurenine 3-monooxygenase — In enzymology, a kynurenine 3 monooxygenase (EC number|1.14.13.9) is an enzyme that catalyzes the chemical reaction:L kynurenine + NADPH + H+ + O2 ightleftharpoons 3 hydroxy L kynurenine + NADP+ + H2OThe 4 substrates of this enzyme are L… …   Wikipedia

  • Kynurenine-oxoglutarate transaminase — In enzymology, a kynurenine oxoglutarate transaminase (EC number|2.6.1.7) is an enzyme that catalyzes the chemical reaction:L kynurenine + 2 oxoglutarate ightleftharpoons 4 (2 aminophenyl) 2,4 dioxobutanoate + L glutamateThus, the two substrates… …   Wikipedia

  • Kynurenine-glyoxylate transaminase — In enzymology, a kynurenine glyoxylate transaminase (EC number|2.6.1.63) is an enzyme that catalyzes the chemical reaction:L kynurenine + glyoxylate ightleftharpoons 4 (2 aminophenyl) 2,4 dioxobutanoate + glycineThus, the two substrates of this… …   Wikipedia

  • Kynurenine 7,8-hydroxylase — In enzymology, a kynurenine 7,8 hydroxylase (EC number|1.14.99.2) is an enzyme that catalyzes the chemical reaction:kynurenate + AH2 + O2 ightleftharpoons 7,8 dihydro 7,8 dihydroxykynurenate + AThe 3 substrates of this enzyme are kynurenate, AH2 …   Wikipedia

  • kynurenine 3-hydroxylase — kyn·ure·nine 3 hy·drox·y·lase (kīn uґrə nēn″ hi drokґsĭ lās) kynurenine 3 monooxygenase …   Medical dictionary

  • kynurenine 3-monooxygenase — kyn·ure·nine 3 mono·oxy·gen·ase (kīn uґrə nēn″ mon″o okґsĭ jən ās) [EC 1.14.13.9] an enzyme of the oxidoreductase class that catalyzes the hydroxylation of kynurenine as a step in the metabolism of… …   Medical dictionary

  • kynurenine — noun A metabolite, 2 amino 4 (2 aminophenyl) 4 oxo butanoic acid, that is an intermediate in the conversion of tryptophan to niacin See Also: kynurenic acid …   Wiktionary

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