kynureninase

A liver enzyme catalyzing the hydrolysis of the l-kynurenine side chain, with the formation of anthranilic acid and l-alanine, in l-tryptophan metabolism.

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kyn·u·ren·i·nase (kīn″u-renґĭ-nās) [EC 3.7.1.3] an enzyme of the hydrolase class that catalyzes the cleavage of hydroxykynurenine to hydroxyanthranilic acid and alanine as a step in the metabolism of tryptophan; kynurenine is also a substrate. The enzyme is a pyridoxal phosphate protein, so enzyme activity is reduced in vitamin B₆ deficiency.