inhibin

inhibin
One of several proteins that participate in differentiation and growth. Two glycoproteins, i. A and i. B, are secreted by Sertoli cells in the testis and granulosa cells in the ovary, inhibiting FSH secretion by direct action on the pituitary. [inhibit + -in]

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in·hib·in in-'hib-ən n a glycoprotein hormone that is secreted by the pituitary gland and in the male by the Sertoli cells and in the female by the granulosa cells and that inhibits the secretion of follicle-stimulating hormone

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in·hib·in (in-hibґin) either of two glycoproteins, A and B, each composed of a common alpha subunit and one of two beta subunits; they are secreted by the gonads and found in seminal plasma and follicular fluid, and inhibit pituitary production of follicle-stimulating hormone. They also contribute to the control of gametogenesis, embryonic and fetal development, and hematopoiesis. They are members of the transforming growth factor-β superfamily of proteins, and their actions are opposed by activins, which share the same beta subunits.

Medical dictionary. 2011.

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  • Inhibin A — Inhibin Beta A Kette (Dimer) Struktur von PDB 2ARV Inhibin ist im menschlichen Organismus ein als Glykoprotein gebildetes Proteohormon, welches in den Sertolizellen der Hoden und in den Granulosazellen der Eierstöcke gebildet wird. Es reguliert… …   Deutsch Wikipedia

  • Inhibin B — Inhibin Beta A Kette (Dimer) Struktur von PDB 2ARV Inhibin ist im menschlichen Organismus ein als Glykoprotein gebildetes Proteohormon, welches in den Sertolizellen der Hoden und in den Granulosazellen der Eierstöcke gebildet wird. Es reguliert… …   Deutsch Wikipedia

  • Inhibin — Beta A Kette (Dimer) Struktur von PDB 2ARV Inhibin ist ein – im menschlichen Organismus – als Glykoprotein gebildetes Proteohormon, welches in den Sertolizellen der Hoden und in den Granulosazellen der Eierstöcke gebildet wird. Es reguliert die… …   Deutsch Wikipedia

  • inhibin — [in hib′in] n. a protein based hormone, produced in small quantities in the testes and ovaries, that inhibits the secretion of FOLLICLE STIMULATING HORMONE …   English World dictionary

  • Inhibin — protein Name = inhibin, alpha caption = width = HGNCid = 6065 Symbol = INHA AltSymbols = EntrezGene = 3623 OMIM = 147380 RefSeq = NM 002191 UniProt = P05111 PDB = ECnumber = Chromosome=2 Arm=q Band=33 qter LocusSupplementaryData = protein Name =… …   Wikipedia

  • inhibin — Polypeptide hormone secreted by the hypophysis, that selectively suppresses the secretion of pituitary FSH (follicle stimulating hormone). The molecule has two subunits (14 and 18 kD), and is a product of the gene family that includes TGF b.… …   Dictionary of molecular biology

  • Inhibin — In|hi|bin [↑ Inhibition u. ↑ in (3)], das; s, e: 1) in den Gonaden produziertes Glykoprotein vom MG 32 000, das in der Hypophyse die Follitropin Sekretion reguliert; 2) veraltete Bez. für nicht charakterisierte u. z. B. im Speichel vermutete… …   Universal-Lexikon

  • inhibin — noun Etymology: Latin inhibēre to inhibit + English 1 in Date: 1932 a glycoprotein hormone that is secreted by the pituitary gland and in the male by the Sertoli cells and in the female by the granulosa cells and that inhibits the secretion of… …   New Collegiate Dictionary

  • inhibin — /in hib in/, Biochem. a hormone, found in semen, that acts on the pituitary gland to decrease FSH. [1980 85; INHIB(IT) + IN2] * * * …   Universalium

  • inhibin — noun A peptide hormone, secreted by the gonads, which inhibits the secretion of follicle stimulating hormone and is thus under consideration as a male contraceptive …   Wiktionary

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