hepatotoxicity

hepatotoxicity
The capacity of a drug, chemical, or other exposure to produce injury to the liver. Agents with recognized h. include carbon tetrachloride, alcohol, dantrolene sodium, valproic acid, isonicotinic acid hydrazide.

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he·pa·to·tox·ic·i·ty -täk-'sis-ət-ē n, pl -ties
1) a state of toxic damage to the liver
2) a tendency or capacity to cause hepatotoxicity

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hep·a·to·tox·ic·i·ty (hep″ə-to-tok-sisґĭ-te) the quality or property of exerting a destructive or poisonous effect upon liver cells.

Medical dictionary. 2011.

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  • Hepatotoxicity — Alternative names Toxic liver disease Toxin induced liver disease Drug induced liver disease Drug induced liver damage Hepatogenous poisoning Subordinate terms Toxic hepatitis Toxin induced hepatitis Drug induced hepatitis Drug induced hepatic… …   Wikipedia

  • hepatotoxicity — noun Date: 1952 1. a state of toxic damage to the liver 2. a tendency or capacity to cause hepatotoxicity …   New Collegiate Dictionary

  • hepatotoxicity — ˌhepəd.ōˌtäkˈsisə̇d.ē noun ( es) Etymology: hepatotoxic + ity 1. : a state of toxic damage to the liver 2. : capacity to cause hepatotoxicity …   Useful english dictionary

  • hepatotoxicity — hep·a·to·tox·ic·i·ty (hĕp ə tō tŏk sĭsʹĭ tē, hĭ păt ō ) n. 1. The quality or condition of being toxic or destructive to the liver. 2. The capacity of a substance to have damaging effects on the liver.   hep a·to·toxʹic ( tŏkʹsĭk) adj. * * * …   Universalium

  • hepatotoxicity — noun toxicity that damages the liver See Also: hepatotoxic …   Wiktionary

  • hepatotoxicity — n. quality of being poisonous to liver cells …   English contemporary dictionary

  • hepatotoxicity — hep·a·to·tox·ic·i·ty …   English syllables

  • Paracetamol hepatotoxicity — is injury to the liver resulting from excessive use of the analgesic drug paracetamol (called acetaminophen in the United States). It is the most common cause of acute liver failure in the United States and the United Kingdom.Damage to the liver …   Wikipedia

  • CIOMS/RUCAM scale — The CIOMS/RUCAM scale is a tool to predict whether liver damage can be attributed to a particular medication.HepatotoxicityDetermining hepatotoxicity (toxic effects of a substance on the liver) remains a major challenge in clinical practice due… …   Wikipedia

  • NNRTI — Nichtnukleosidische Reverse Transkriptase Inhibitoren (engl. Non Nucleoside Reverse Transcriptase Inhibitor, NNRTI) sind Arzneistoffe aus der Gruppe der Virustatika. Der erste Wirkstoff wurde 1990 entwickelt. Es handelt sich um Wirkstoffe, die… …   Deutsch Wikipedia

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