A class of drugs, including phenoxybenzamine and diabenamine, which binds so as to alkylate α-adrenergic receptors so that they are irreversibly inactivated.

Medical dictionary. 2011.

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  • phenoxybenzamine hydrochloride — A potent nonselective adrenergic (α receptor) blocking agent of the β haloalkylamines; blocks the excitatory response of smooth muscle and exocrine glands to epinephrine; used in the treatment of peripheral …   Medical dictionary

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