- unbalanced translocation
- translocation that results in a net gain or loss of chromosomal material, usually with serious clinical effects and often incompatible with life.
Medical dictionary. 2011.
unbalanced translocation
Look at other dictionaries:
translocation — 1. Transposition of two segments between nonhomologous chromosomes as a result of abnormal breakage and refusion of reciprocal segments. 2. Transport of a metabolite across a biomembrane. [trans + L. location, placement, fr. loco, to place]… … Medical dictionary
Translocation, Robertsonian — A relatively very common and medically significant type of chromosome rearrangement that is formed by fusion of the whole long arms of two acrocentric chromosomes (chromosomes with the centromere near the very end). One in about 900 babies is… … Medical dictionary
balanced translocation — translocation that results in no more or no less than the normal chromosomal complement. The phenotype is usually normal, but there will be partial aneuploidy in a percentage of the gametes, with a risk of an unbalanced chromosomal complement in… … Medical dictionary
Chromosomal translocation — of the 4th and 20th chromosome. In genetics, a chromosome translocation is a chromosome abnormality caused by rearrangement of parts between nonhomologous chromosomes. A gene fusion may be created when the translocation joins two otherwise… … Wikipedia
Robertsonian translocation — is a common form of chromosomal rearrangement that occurs in the five acrocentric human chromosome pairs, namely 13, 14, 15, 21, and 22. They are named after the American insect geneticist W. R. B. Robertson, who first described a Robertsonian… … Wikipedia
Robertsonian translocation — A common and significant type of chromosome rearrangement that is formed by fusion of the whole long arms of two acrocentric chromosomes (chromosomes with the centromere near the very end). One in about 900 babies is born with a Robertsonian… … Medical dictionary
Centric-fusion translocation — A type of chromosome rearrangement, also called a Robertsonian translocation, in which there is fusion of an entire long arm of one acrocentric chromosome with a similarly intact long arm of another acrocentric chromosome. The short arms of the… … Medical dictionary
Whole-arm translocation — A type of chromosome rearrangement, also called a Robertsonian translocation, in which there is fusion of an entire long arm of one acrocentric chromosome with a similarly intact long arm of another acrocentric chromosome. The short arms of the… … Medical dictionary
Jacobsen syndrome — Infobox Disease Name = Jacobsen syndrome Caption = DiseasesDB = 31957 ICD10 = ICD10|Q|93|5|q|90 ICD9 = ICD9|757.3 ICDO = OMIM = 147791 MedlinePlus = eMedicineSubj = eMedicineTopic = MeshName = MeshNumber = Jacobsen Syndrome, also known as 11q… … Wikipedia
Aneuploidy — Classification and external resources ICD 10 Q90 Q98 ICD 9 … Wikipedia
