gas gangrene toxin

gas gangrene toxin
any of the exotoxins produced by Clostridium perfringens and associated with gas gangrene. At least 10 types have been identified. The α toxin is a lethal, necrotizing lecithinase (phospholipase-C) that splits lecithin in cell membranes, is hemolytic, and causes capillary damage. C. novyi and C. septicum produce similar toxins that cause gas gangrene.

Medical dictionary. 2011.

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  • Gas gangrene — Classification and external resources Photograph before right leg amputation (hemipelvectomy) of a patient with gas gangrene. The right thigh is swollen, edematous and discoloured with necrotic bullae (large blisters). An impressive crepitation… …   Wikipedia

  • gas gangrene — n progressive gangrene marked by impregnation of the dead and dying tissue with gas and caused by one or more toxin producing bacteria of the genus Clostridium that enter the body through wounds and proliferate in necrotic tissue * * * death and… …   Medical dictionary

  • gas gangrene — noun Date: 1914 progressive gangrene marked by impregnation of the dead and dying tissue with gas and caused by one or more toxin producing clostridia …   New Collegiate Dictionary

  • gangrene — gangrenous /gang greuh neuhs/, adj. /gang green, gang green /, n., v., gangrened, gangrening. Pathol. n. 1. necrosis or death of soft tissue due to obstructed circulation, usually followed by decomposition and putrefaction. v.t., v.i. 2. to… …   Universalium

  • clostridial toxin — a toxin elaborated by species of Clostridium, such as botulinus toxin, gas gangrene toxin, or tetanus toxin. C. difficile also produces an exotoxin that causes intestinal necrosis, and C. perfringens produces exotoxins that cause gas gangrene,… …   Medical dictionary

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  • Clostridium septicum — Scientific classification Domain: Bacteria Division …   Wikipedia

  • Clostridium — A group of anaerobic bacteria (bacteria that thrive in the absence of oxygen). There are 100+ species of Clostridium. They include, for examples, Clostridium difficile, Clostridium perfringens (also called Clostridium welchii), and Clostridium… …   Medical dictionary

  • Antitoxin — An antibody capable of destroying microorganisms including viruses and bacteria. An antitoxin provides passive immunity. For example, if a child gets whooping cough (diphtheria), an antitoxin prepared in horses against diphtheria may be useful in …   Medical dictionary

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