lepromin test

lepromin test
(for certain types of leprosy) after intradermal injection of lepromin (q.v.), a positive reaction consists of either a tuberculin-type reaction at 48 to 72 hours (Fernandez reaction) or a nodular, occasionally ulcerated, lesion at 3 to 4 weeks (Mitsuda reaction). The test is not diagnostic; a large fraction of the normal population exhibits positive reactivity owing to sensitivity to cross-reacting antigens. In individuals known to have leprosy, a positive result on this test is indicative of tuberculoid or borderline tuberculoid leprosy, and lack of reactivity is indicative of lepromatous or borderline lepromatous leprosy.

Lepromin test; positive reaction at four weeks.

Medical dictionary. 2011.

Look at other dictionaries:

  • lepromin — An extract of tissue infected with Mycobacterium leprae used in skin tests to classify the stage of leprosy. SEE ALSO: l. reaction, test. * * * lep·ro·min le prō mən n an extract of human leprous tissue used in a skin test for leprosy infection… …   Medical dictionary

  • lepromin reaction — either of the results of a lepromin test; see Fernandez r. and Mitsuda r …   Medical dictionary

  • test — 1. To prove; to try a substance; to determine the chemical nature of a substance by means of reagents. 2. A method of examination, as to determine the presence or absence of a definite disease or of some substance in any of the fluids, tissues,… …   Medical dictionary

  • Lepromin — The lepromin skin test is used to determine what type of leprosy a person has. It involves the injection of a standardized extract of the inactivated leprosy bacillus ,( Mycobacterium leprae or Hansen s Bacillus ) under the skin. It is not… …   Wikipedia

  • lepromin — leˈprōmə̇n noun ( s) Etymology: New Latin leproma + English in : an extract of human leprous tissue used in a skin test for leprosy infection …   Useful english dictionary

  • Mitsuda antigen reaction test — Mit·su·da antigen, reaction, test (mitґsoo dah″) [Kensuke Mitsuda, Japanese physician, 1876–1964] see under reaction; see lepromin; and see lepromin test, under test …   Medical dictionary

  • Mitsuda test — lepromin t …   Medical dictionary

  • reaction — 1. The response of a muscle or other living tissue or organism to a stimulus. 2. The color change effected in litmus and certain other organic pigments by contact with substances such as acids or alkalies; also the property that such substances… …   Medical dictionary

  • antigen — Any substance that, as a result of coming in contact with appropriate cells, induces a state of sensitivity and/or immune responsiveness after a latent period (days to weeks) and that reacts in a demonstrable way with antibodies and/or immune… …   Medical dictionary

  • Leprosy — A chronic granulomatous infection caused by a bacillus (bacterium) that affects various areas of the body, particularly the skin and nerves. (Granulomas are inflammatory nodules that are usually small, granular, firm, and persistent.) The… …   Medical dictionary

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