properdin system

properdin system
former name for the alternative complement pathway.

Medical dictionary. 2011.

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  • properdin — ☆ properdin [prō pʉrd′ n ] n. 〚/span> PRO(TEIN) + L perdere, to destroy + IN1〛 a protein present in blood serum and active in the destruction of bacteria and the neutralization of viruses * * * pro·per·din (prō pûrʹdn) n. A protein in …   Universalium

  • Properdin — protein Name = complement factor properdin caption = width = HGNCid = 8864 Symbol = CFP AltSymbols = PFC EntrezGene = 5199 OMIM = 300383 RefSeq = NM 002621 UniProt = P27918 PDB = ECnumber = Chromosome = X Arm = p Band = 11.4… …   Wikipedia

  • system — 1. [TA] A consistent and complex whole made up of correlated and semiindependent parts. A complex of functionally related anatomic structures. 2. The entire organism seen as a complex organization of parts. 3. Any complex of structures… …   Medical dictionary

  • properdin — A globulin in normal serum involved in resistance to infection that participates, in conjunction with other factors, in an alternative pathway to the activation of the terminal components of complement; a deficiency of p. results in the lack of… …   Medical dictionary

  • properdin — noun A protein in human serum that complements part of the immune system …   Wiktionary

  • Complement system — This article is about an aspect of the immune system. For other uses, see complement (disambiguation). The complement system helps or “complements” the ability of antibodies and phagocytic cells to clear pathogens from an organism. It is part of… …   Wikipedia

  • Louis Pillemer — (1908 August 31 1957), was an American immunologist, an early investigator of the alternative complement pathway (a system of defense not dependent upon antibodies.)He led a team at Western Reserve University which discovered properdin in 1954,… …   Wikipedia

  • factor — 1. One of the contributing causes in any action. 2. One of the components that by multiplication makes up a number or expression. 3. SYN: gene. 4. A vitamin or other essential element. 5. An event, characteristic, or other definable entity that …   Medical dictionary

  • complement — Ehrlich term for the thermolabile substance, normally present in serum, that is destructive to certain bacteria and other cells sensitized by a specific c. fixing antibody. C. is a group of at least 20 distinct serum proteins, the …   Medical dictionary

  • complement — complementer, n. n. /kom pleuh meuhnt/; v. /kom pleuh ment /, n. 1. something that completes or makes perfect: A good wine is a complement to a good meal. 2. the quantity or amount that completes anything: We now have a full complement of packers …   Universalium

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