nephrogenic syndrome of inappropriate antidiuresis

nephrogenic syndrome of inappropriate antidiuresis
(NSIAD) a hyponatremic syndrome, clinically resembling the syndrome of inappropriate diuretic hormone, caused by inability of the renal collecting tubules to absorb water in response to antidiuretic hormone. Type I, which accounts for 90 percent of cases, is an X-linked syndrome caused by loss of vasopressin receptor function as a result of mutations in the gene encoding the receptors (locus: Xq28). Type II is caused by a mutation in the gene encoding aquaporin-2 (locus: 12q13); inheritance may be autosomal dominant or recessive.

Medical dictionary. 2011.

Игры ⚽ Поможем сделать НИР

Look at other dictionaries:

  • syndrome of inappropriate antidiuresis — (SIAD) a disorder of sodium and water balance characterized by hyponatremia with hypovolemia and elevated urine osmolality in the absence of kidney disease; it may be caused by inappropriate secretion of vasopressin (s. of inappropriate… …   Medical dictionary

  • NSIAD — nephrogenic syndrome of inappropriate antidiuresis …   Medical dictionary

  • Demeclocycline — Systematic (IUPAC) name (2E,4S,4aS,5aS,6S,12aS) 2 [amino(hydroxy)methylidene] 7 chloro 4 (dimethylamino) 6,10,11,12a tetrahydroxy 1,2,3,4,4a,5,5a,6,12,12a decahydrotetracene 1,3,12 trione …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”