mastocytosis syndrome

mastocytosis syndrome
an episodic syndrome occurring in certain patients with systemic mastocytosis, usually those with skin lesions, bone lesions, and hepatosplenomegaly, presumably associated with histamine release from degranulation of mast cells, and characterized mainly by intense pruritus, flushing, headache, tachycardia, hypotension, and syncope.

Medical dictionary. 2011.

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