Chromosome inversion

Chromosome inversion
A chromosome segment is clipped out, turned upside down and reinserted back into the chromosome. A chromosome inversion can be inherited and have come from one of the parents to a child. Or the inversion can appear for the first time in a child. An inversion can be "balanced", meaning that it has all the genes present in the normal uninverted chromosome. Or an inversion can be "unbalanced", meaning that genes been have deleted (lost) or duplicated. A balanced inversion in a child causes no problems. An unbalanced inversion is abnormal and is often associated with problems such as development delay (and later, mental retardation) and multiple congenital anomalies (birth defects). Inversions can also be acquired in a body cell (a somatic cell) and be a step involving that cell in a precancerous and cancerous process.

Medical dictionary. 2011.

Игры ⚽ Поможем написать реферат

Look at other dictionaries:

  • Chromosome inversion, paracentric — A basic type of chromosome rearrangement. A segment that does not include the centromere (and so is paracentric) has been snipped out of a chromosome, turned through 180 degrees (inverted), and inserted right back into its original location in… …   Medical dictionary

  • Chromosome inversion, pericentric — A basic type of chromosome rearrangement in which a segment that includes the centromere (and so is pericentric) has been snipped out of a chromosome, turned through 180 degrees (inverted), and inserted back into its original location in… …   Medical dictionary

  • Paracentric chromosome inversion — A basic type of chromosome rearrangement. A segment that does not include the centromere (and so is paracentric) has been snipped out of a chromosome, turned through 180 degrees (inverted), and inserted right back into its original location in… …   Medical dictionary

  • Pericentric chromosome inversion — A basic type of chromosome rearrangement in which a segment that includes the centromere (and so is pericentric) has been snipped out of a chromosome, turned through 180 degrees (inverted), and inserted back into its original location in… …   Medical dictionary

  • Chromosome — For a non technical introduction to the topic, see Introduction to genetics. Diagram of a replicated and condensed metaphase eukaryotic chromosome. (1) Chromatid – one of the two identical parts of the chromosome after S phase. (2)… …   Wikipedia

  • Inversion, paracentric chromosome — A basic type of chromosome rearrangement in which a segment that does not include the centromere (and so is paracentric) has been snipped out of a chromosome, turned through 180 degrees (inverted), and inserted right back into its original… …   Medical dictionary

  • Inversion, pericentric chromosome — A basic type of chromosome rearrangement in which a segment that includes the centromere (and so is pericentric) has been snipped out of a chromosome, turned through 180 degrees (inverted), and inserted back into its original location in… …   Medical dictionary

  • Inversion, chromosome — A chromosome segment is clipped out, turned upside down and reinserted back into the chromosome. A chromosome inversion can be inherited and have come from one of the parents to a child. Or the inversion can appear for the first time in a child.… …   Medical dictionary

  • Chromosome engineering — is the controlled generation of chromosomal deletions, inversions, or translocations with defined endpoints. [1] By combining chromosomal translocation, chromosomal inversion,and chromosomal deletion, chromosome engineering has been shown to… …   Wikipedia

  • inversion — [ ɛ̃vɛrsjɔ̃ ] n. f. • 1529; lat. inversio, de invertere « retourner » I ♦ A ♦ Sens spéciaux 1 ♦ Déplacement (d un mot ou d un groupe de mots) par rapport à l ordre normal ou habituel de la construction. Inversion du sujet dans l interrogation (ex …   Encyclopédie Universelle

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”