Medical dictionary. 2011.
Small interfering RNA — (siRNA), sometimes known as short interfering RNA or silencing RNA, is a class of 20 25 nucleotide long double stranded RNA molecules that play a variety of roles in biology. Most notably, siRNA is involved in the RNA interference (RNAi) pathway … Wikipedia
Small interfering RNA — Aufbau der siRNA Small interfering RNA (kurz siRNA) sind kurze, einzelsträngige oder doppelsträngige Ribonukleinsäure Moleküle. Sie codieren kein Protein, spielen aber insbesondere im Rahmen der RNA Interferenz in den Zellen von Lebewesen mit… … Deutsch Wikipedia
Small interfering RNA — Малые интерферирующие РНК (siRNA, small interfering RNA), также известные как короткие интерферирующие РНК, или silencing RNA это класс двуцепочечных РНК, длиной 20 25 нуклеотидов. siRNA вовлечены в процесс РНК интерференции (RNAi), в котором… … Википедия
Small interfering RNA — ARN interférent Protéine DICER L expression ARN interférent désigne un acide ribonucléique simple ou double brin, qui interfère avec un ARN messager spécifique conduisant à sa dégradation et à la diminution de sa traduction en protéine. Sommaire … Wikipédia en Français
Small hairpin RNA — A small hairpin RNA or short hairpin RNA (shRNA) is a sequence of RNA that makes a tight hairpin turn that can be used to silence gene expression via RNA interference. shRNA uses a vector introduced into cells and utilizes the U6 promoter to… … Wikipedia
RNA interference — (RNAi) is a mechanism that inhibits gene expression at the stage of translation or by hindering the transcription of specific genes. RNAi targets include RNA from viruses and transposons (significant for some forms of innate immune response), and … Wikipedia
RNA-induced silencing complex — RNA induced silencing complex, or RISC, is a multi protein siRNA complex which cleaves (incoming viral) dsRNA and binds short antisense RNA strands which are then able to bind complementary strands. When it finds the complementary strand, it… … Wikipedia
RNA-dependent RNA polymerase — (RDRP), or RNA replicase, is an enzyme that catalyzes the replication of RNA from an RNA template. This is in contrast to a typical RNA polymerase, which catalyzes the transcription of RNA from a DNA template.Viral RDRPs were discovered in the… … Wikipedia
RNA-induced transcriptional silencing — (RITS) is a form of RNA interference by which short RNA molecules such as small interfering RNA (siRNA) trigger the downregulation of transcription of a particular gene or genomic region. This is usually accomplished by posttranslational… … Wikipedia
RNA silencing — refers to a family of gene silencing effects by which the expression of one or more genes is downregulated or entirely suppressed by the introduction of an antisense RNA molecule. The most common and well studied example is RNA interference, in… … Wikipedia
