pyruvate dehydrogenase (acetyl-transferring)
- pyruvate dehydrogenase (acetyl-transferring)
- py·ru·vate de·hy·dro·gen·ase (ac·e·tyl-trans·fer·ring) (piґroo-vāt de-hiґdro-jən-ās asґə-təl transґfər-ing) [EC 1.2.4.1] an enzyme of the oxidoreductase class that is a component of the multienzyme pyruvate dehydrogenase complex (q.v.). The enzyme catalyzes the oxidative decarboxylation of pyruvate, forming acetyl bound to the cofactor thiamine pyrophosphate; the acetyl is subsequently transferred to the lipoamide linked to the side chain of a lysine residue of the enzyme dihydrolipoyllysine-residue acetyltransferase, which is also part of the complex. Deficiency of the enzyme causes lacticacidemia, ataxia, psychomotor retardation, and sometimes lactic acidosis.
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Pyruvate dehydrogenase (acetyl-transferring) — In enzymology, a pyruvate dehydrogenase (acetyl transferring) (EC number|1.2.4.1) is an enzyme that catalyzes the chemical reaction:pyruvate + [dihydrolipoyllysine residue acetyltransferase] lipoyllysine ightleftharpoons [dihydrolipoyllysine… … Wikipedia
(pyruvate dehydrogenase (acetyl-transferring))-phosphatase — In enzymology, a [pyruvate dehydrogenase (acetyl transferring)] phosphatase (EC number|3.1.3.43) is an enzyme that catalyzes the chemical reaction: [pyruvate dehydrogenase (acetyl transferring)] phosphate + H2O ightleftharpoons [pyruvate… … Wikipedia
[pyruvate dehydrogenase (acetyl-transferring)] kinase — [py·ru·vate de·hy·dro·gen·ase (ac·e·tyl trans·fer·ring)] ki·nase (piґroo vāt de hiґdro jən ās asґə təl transґfər ing kiґnās) [EC 2.7.11.2] an enzyme of the transferase class that catalyzes the phosphorylation of … Medical dictionary
[pyruvate dehydrogenase (acetyl-transferring)]-phosphatase — [py·ru·vate de·hy·dro·gen·ase (ac·e·tyl trans·fer·ring)] phos·pha·tase (piґroo vāt de hiґdro jən ās asґə təl transґfər ing fosґfə tās) [EC 3.1.3.43] an enzyme of the hydrolase class that catalyzes the… … Medical dictionary
Pyruvate dehydrogenase (lipoamide) alpha 1 — PDB rendering based on 1ni4 … Wikipedia
pyruvate dehydrogenase complex — a multienzyme complex consisting of multimers of the three distinct enzymes: pyruvate dehydrogenase (acetyl transferring) [EC 1.2.4.1], dihydrolipoyllysine residue acetyltransferase [EC 2.3.1.12], and dihydrolipoyl dehydrogenase [EC 1.8.1.4]. The … Medical dictionary
Pyruvate dehydrogenase complex — (PDC) is a complex of three enzymes that transform pyruvate into acetyl CoA by a process called pyruvate decarboxylation. Acetyl CoA may then be used in the citric acid cycle to carry out cellular respiration, and this complex links the… … Wikipedia
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NADH dehydrogenase — Structure of NADH dehydrogenase Identifiers EC number 1.6.5.3 … Wikipedia
Malate dehydrogenase — Structure of the protein with attached sugars Identifiers EC number … Wikipedia
