exogenous pyrogen

exogenous pyrogen
a fever-producing agent of external origin; types include bacterial endotoxins and other microbial products, certain types of antigen-antibody complexes, viruses, synthetic polynucleotides, incompatible blood and blood products, and androgen breakdown products such as etiocholanone. The action is mediated by an endogenous pyrogen.

Medical dictionary. 2011.

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  • pyrogen — A fever inducing agent; pyrogens are produced by bacteria, molds, viruses, and yeasts. [pyro + G. gen, producing] endogenous p. (EP) proteins that induce fever. Several (about 11) have been identified, including cytokines formed by components of… …   Medical dictionary

  • Fever — (also known as pyrexia, from the Greek pyretos meaning fire, or a febrile response, from the Latin word febris , meaning fever, and archaically known as ague) is a frequent medical sign that describes an increase in internal body temperature to… …   Wikipedia

  • Depyrogenation — refers to the removal of pyrogens from solution, most commonly from injectable pharmaceuticals. A pyrogen is defined as any substance that can cause a fever. Bacterial pyrogens include endotoxins and exotoxins, although many pyrogens are… …   Wikipedia

  • Lipopolysaccharide — Structure of a lipopolysaccharide Lipopolysaccharides (LPS), also known as lipoglycans, are large molecules consisting of a lipid and a polysaccharide joined by a covalent bond; they are found in the outer membrane of Gram negative bacteria, act… …   Wikipedia

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