p53 protein

p53 protein
a DNA-binding nuclear protein that regulates transcription of several other genes, playing an essential role in cell-cycle arrest and apoptosis in response to DNA damage or conditions of cellular stress by causing arrest in G1 phase and inducing transcription of DNA repair genes; it is undetectable or present at very low levels in normal resting cells but present at high levels in a wide variety of transformed cells.

Medical dictionary. 2011.

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