p53 gene

p53 gene
a tumor suppressor gene that encodes the DNA-binding p53 protein (q.v.). Mutations have been associated with malignant transformation of cells, including germline mutations in Li-Fraumeni syndrome and sporadic somatic mutations.

Medical dictionary. 2011.

Игры ⚽ Нужно сделать НИР?

Look at other dictionaries:

  • p53 gene — A human tumour suppressor transcription factor gene, damage or mutation to which is believed to be responsible for up to 60% of all human cancer tumours. If, in spite of the presence of p53 protein, a cell begins to divide uncontrollably… …   Glossary of Biotechnology

  • p53 gene — A tumor suppressor gene that normally inhibits the growth of tumors. This gene is altered in many types of cancer …   English dictionary of cancer terms

  • P53 — (also known as protein 53 or tumor protein 53), is a transcription factor encoded by the TP53 gene. p53 is important in multicellular organisms, where it regulates the cell cycle and thus functions as a tumor suppressor that is involved in… …   Wikipedia

  • P53 — Bänder /Oberflächenmodell vpn p53 an DNA nach PDB  …   Deutsch Wikipedia

  • p53 — Bänder /Oberflächenmodell von p53 an DNA nach PDB  …   Deutsch Wikipedia

  • p53 — For the band and album of the same name, see P53 (band) and P53 (album). Tumor protein p53 PDB rendering based on 1TUP …   Wikipedia

  • p53 upregulated modulator of apoptosis — BCL2 binding component 3 Identifiers Symbols BBC3; FLJ42994; JFY1; PUMA External IDs …   Wikipedia

  • p53 — A tumor suppressor. The designation p53 stands for protein 53 kilodaltons in size. p53 is a specific protein produced by a gene that functions to suppress the growth of tumors. The p53 gene is the most commonly mutated gene known in human cancer …   Medical dictionary

  • P53 — est une protéine impliquée dans certains cancers. Sommaire 1 Historique 1.1 De 1979 à 1985 1.2 1985 1989 1.3 1989 2007 …   Wikipédia en Français

  • Gene suppresseur de tumeurs — Gène suppresseur de tumeurs Un gène suppresseur de tumeurs est un régulateur négatif de la prolifération cellulaire. Sommaire 1 Introduction 2 Les gènes suppresseurs de tumeurs 3 Cancers héréditaires …   Wikipédia en Français

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”