protamine sulfate

protamine sulfate
[USP] a purified mixture of simple protein principles obtained from the sperm or testes of suitable species of fish and able to neutralize heparin; used as an antidote to overdosage with heparin, administered intravenously.

Medical dictionary. 2011.

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  • Protamine sulfate — is a drug that reverses the anticoagulant effects of heparin by binding to it. Protamine was formerly isolated from the sperm of various fish, but is now produced through recombinant biotechnology. It is a highly cationic peptide. It binds to… …   Wikipedia

  • Protamine — protein Name=protamine 1 caption= width= HGNCid=9447 Symbol=PRM1 AltSymbols= EntrezGene=5619 OMIM=182880 RefSeq=NM 002761 UniProt=P04553 PDB= ECnumber= Chromosome=16 Arm=p Band=13.13 LocusSupplementaryData=protein Name=protamine 2 caption= width …   Wikipedia

  • protamine — /proh teuh meen , pro tam in/, n. Biochem. any of a group of arginine rich, strongly basic proteins that are not coagulated by heat, occurring primarily in the sperm of fish. [1870 75; PROT + AMINE] * * * ▪ protein       simple alkaline protein… …   Universalium

  • Protamine — Les protamines sont des petites protéines nucléaires riches en arginine, qui remplacent des protéines de transition qui avaient remplacé les histones des futurs gamètes mâles pendant la phase précoce de la spermiogenèse. On pense que ce… …   Wikipédia en Français

  • protamine — Any of a class of proteins, highly basic because rich in l arginine and simpler in constitution than the albumins and globulins, etc., found in fish spermatozoa in combination with nucleic acid; the protamines have a histonelike function and are… …   Medical dictionary

  • Copper(II) sulfate — Crystal of CuSO4·5H2O Anhydrous CuSO4 powder …   Wikipedia

  • Low molecular weight heparin — In medicine, low molecular weight heparin (LMWH) is a class of medication used as an anticoagulant in diseases that feature thrombosis, as well as for prophylaxis in situations that lead to a high risk of thrombosis.[1] Thrombotic disease or… …   Wikipedia

  • Heparin — Systematic (IUPAC) name see Hep …   Wikipedia

  • Antidote — For other uses, see Antidote (disambiguation). An antidote is a substance which can counteract a form of poisoning.[1] The term ultimately derives from the Greek αντιδιδοναι antididonai, given against . The antidotes for some particular toxins… …   Wikipedia

  • ПРОТАМИНА СУЛЬФАТ — Действующее вещество ›› Протамина сульфат* (Protamine sulfate*) Латинское название Protamine sulfate АТХ: ›› V03AB14 Протамина сульфат Фармакологическая группа: Коагулянты (в т.ч. факторы свертывания крови), гемостатики Нозологическая… …   Словарь медицинских препаратов

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