antigen presentation

antigen presentation
the ingesting and partial digestion of antigens by macrophages, which then present the processed antigen on their surfaces to B and T lymphocytes. (See antigen-presenting cells, under cell.) The presented antigen is more immunogenic than unprocessed antigen, possibly because it has been broken down into pieces more easily recognized by B and T cells, because it remains on the surface of the presenting cell for a long time, or because it is presented in association with self MHC antigen and thus able to stimulate helper T cells.

Medical dictionary. 2011.

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  • Antigen presentation — is a process in the body s immune system by which macrophages, dendritic cells and other cell types capture antigens and then enable their recognition by T cells. NOTOC The basis of adaptive immunity lies in the capacity of immune cells to… …   Wikipedia

  • antigen presentation — See antigen presenting cell …   Dictionary of molecular biology

  • Antigen processing — is a biological process that prepares antigens for presentation to special cells of the immune system called T lymphocytes. This process involves two distinct pathways for processing of antigens from an organism s own (self) proteins or… …   Wikipedia

  • Antigen — Each antibody binds to a specific antigen; an interaction similar to a lock and key. An antigen is a foreign molecule that, when introduced into the body, triggers the production of an antibody by the immune system. The immune system will then… …   Wikipedia

  • Antigen-presenting cell — An antigen presenting cell (APC) or accessory cell is a cell that displays foreign antigen complexed with MHC on its surface. T cells may recognize this complex using their T cell receptor (TCR). Types APCs fall into two categories: professional… …   Wikipedia

  • antigen-presenting cells — cells that take part in antigen presentation (see under presentation); a group of dendritic cells that arise in the bone marrow and migrate to other body sites. They process antigens and put them on their surfaces to react with lymphocytes and… …   Medical dictionary

  • Antigen-presenting cell — Cellule présentatrice d antigène Pour les articles homonymes, voir CPA et APC. Les cellules présentatrices d antigène ou CPA (Antigen presenting cell ou APC en anglais) sont des cellules qui présentent des parties d éléments intrus. Elles peuvent …   Wikipédia en Français

  • presentation — That part of the fetus presenting at the superior strait of the maternal pelvis; occiput, chin, and sacrum are, respectively, the determining points in vertex, face, and breech p.. SEE ALSO …   Medical dictionary

  • Cross-presentation — The term cross presentation denotes the ability of certain antigen presenting cells to take up, process and present extracellular antigens with MHC class I molecules to CD8 T cells (cytotoxic T cells). Cross priming describes the stimulation of… …   Wikipedia

  • Human leukocyte antigen — The human leukocyte antigen system (HLA) is the name of the major histocompatibility complex (MHC) in humans. The superlocus contains a large number of genes related to immune system function in humans. This group of genes resides on chromosome 6 …   Wikipedia

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