phosphoinositide phospholipase C
- phosphoinositide phospholipase C
- phos·pho·ino·si·tide phos·pho·lip·ase C (fos″fo-in-oґsĭ-tīd fos″fo-lipґās) [EC 3.1.4.11] an enzyme of the hydrolase class that catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate to generate inositol 1,4,5-triphosphate and diacylglycerol, second messengers that initiate a cascade of intracellular responses resulting in cell growth and differentiation and gene expression. The enzyme can also act on phosphatidylinositol, carrying out the reaction formerly ascribed to the enzyme officially called 1-phosphatidylinositol phosphodiesterase (q.v.). See also phospholipase C.
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Phosphoinositide phospholipase C — Pfam box Symbol = PI PLC X Name = Phosphatidylinositol specific phospholipase C width = 220px caption =Phospholipase Cδ 1 Pfam= PF00388 InterPro= IPR000909 SMART= PLCXc PROSITE = PDOC50007 SCOP = 1gym TCDB = OPM family= 126 OPM protein= 2plc… … Wikipedia
Phospholipase C — is a class of enzymes that cleave phospholipids just before the phosphate group (see Figure). It is most commonly taken to be synonymous with the human forms of this enzyme, EC number|3.1.4.11, which plays an important role in eukaryotic cell… … Wikipedia
phospholipase C — [EC 3.1.4.3] any esterase that catalyzes the hydrolysis of the phosphoric ester bond of a membrane phospholipid, generating a phosphorylated alcohol and diacylglycerol. Important in the digestion of dietary phospholipids and in various processes… … Medical dictionary
Hydrolase — Cristal de lysozyme Les hydrolases constituent une classe d enzymes qui catalysent les réactions d hydrolyse de molécules suivant la réaction générale : R R + H2O ⇌ R OH + R H On y trouve par exemple les estérases, qui hydrolysent les … Wikipédia en Français
EC 3.1 — Le groupe EC3.1 est un groupe d hydrolases rassemblant les estérases, c est à dire les enzymes catalysant la réaction générale : R O R + H2O ⇌ R OH + R OH où R représente un acide quelconque et R son substrat. En fonction du milieu, l ester… … Wikipédia en Français
List of EC numbers (EC 3) — This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 3.1: Acting on Ester BondsEC… … Wikipedia
Phosphatidylcholine — Phosphatidylcholines (PC) are a class of phospholipids that incorporate choline as a headgroup. They are a major component of biological membranes and can be easily obtained from a variety of readily available sources such as egg yolk or soy… … Wikipedia
Diglyceride — 1 Palmitoyl 2 oleoyl glycerol A diglyceride, or a diacylglycerol (DAG), is a glyceride consisting of two fatty acid chains covalently bonded to a glycerol molecule through ester linkages. One example, shown on the right, is 1 palmitoyl 2 oleoyl… … Wikipedia
Dual-specificity kinase — Identifiers EC number 2.7.12.1 CAS number 134549 83 0 … Wikipedia
1-phosphatidylinositol phosphodiesterase — 1 phos·pha·ti·dyl·ino·si·tol phos·pho·di·es·ter·ase (fos″fə ti″dəl ĭ noґsĭ tol fos″fo di esґtər ās) former official nomenclature for a phospholipase C specific for phosphoinositides, catalyzing the… … Medical dictionary
