diffuse sclerosing osteomyelitis

diffuse sclerosing osteomyelitis
a chronic diffuse inflammatory response of bone to low-grade infection, with inflammatory cell infiltrate, fibrous replacement of marrow, and dense sclerotic masses of trabecular bone. Polymorphonuclear leukocytes, plasma cells, and focal osteoblasts may be present. Oral lesions occur predominantly in the mandible of older persons and are often sequelae of chronic periodontal disease.

Medical dictionary. 2011.

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