non-Hodgkin lymphoma

non-Hodgkin lymphoma
a heterogeneous group of malignant lymphomas, the only common feature being an absence of the giant Reed-Sternberg cells characteristic of Hodgkin disease. They arise from the lymphoid components of the immune system, and present a clinical picture broadly similar to that of Hodgkin disease except the disease is initially more widespread, with the most common manifestation being painless enlargement of one or more peripheral lymph nodes. There have been numerous classifications of the non-Hodgkin lymphomas; the most recent system is the Revised European-American Lymphoma (REAL) Classification (see under classification).

Medical dictionary. 2011.

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