iodotyrosine deiodinase

iodotyrosine deiodinase
io·do·ty·ro·sine de·io·din·ase (i″o-do-tiґro-sēn de-iґo-dĭ-nās) an enzyme that catalyzes the removal of iodine from monoiodotyrosine and diiodotyrosine. The reaction is a step in the conservation of iodine by the thyroid. Congenital deficiency of the enzyme results in severe loss of iodine, resulting in hypothyroidism and goiter. Called also iodotyrosine dehalogenase.

Medical dictionary. 2011.

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  • iodotyrosine dehalogenase — io·do·ty·ro·sine de·hal·o·gen·ase (i o″do tiґro sēn de halґo jən ās) iodotyrosine deiodinase …   Medical dictionary

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  • goiter — A chronic enlargement of the thyroid gland, not due to a neoplasm, occurring endemically in certain localities, especially regions where glaciation occurred and the soil is low in iodine, and sporadically elsewhere. SYN: struma (1). [Fr. from L.… …   Medical dictionary

  • Congenital hypothyroidism — Classification and external resources ICD 10 E00, E03.0, E03.1 …   Wikipedia

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