iodide peroxidase

iodide peroxidase
io·dide per·ox·i·dase (iґo-dīd pər-okґsĭ-dās) [EC 1.11.1.8] an enzyme of the oxidoreductase class that catalyzes a series of reactions occurring in the synthesis of thyroxine; it catalyzes the oxidation of iodide to iodine, the iodination of tyrosyl residues of thyroglobulins, and the intramolecular condensation of such iodinated residues to form iodothyronines. Deficiency of the enzyme, an autosomal recessive disorder, results in congenital goiter. Called also thyroid peroxidase and thyroperoxidase.

Medical dictionary. 2011.

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  • thyroid peroxidase — thy·roid per·ox·i·dase (thiґroid pər okґsĭ dās) iodide peroxidase …   Medical dictionary

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  • hormone — hormonal, hormonic /hawr mon ik, moh nik/, adj. /hawr mohn/, n. 1. Biochem. any of various internally secreted compounds, as insulin or thyroxine, formed in endocrine glands, that affect the functions of specifically receptive organs or tissues… …   Universalium

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  • Deiodinase — (or iodide peroxidase or Monodeiodinase ) is a peroxidase enzyme that is involved in the activation or deactivation of thyroid hormones. In general, T4 (thyroxine) is converted into T3 (triiodothyronine) by the deiodinase enzyme in target cells.… …   Wikipedia

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  • deiodinase — noun Iodide peroxidase, an enzyme …   Wiktionary

  • iodinase — SYN: iodide peroxidase …   Medical dictionary

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