iodide peroxidase

iodide peroxidase
io·dide per·ox·i·dase (iґo-dīd pər-okґsĭ-dās) [EC 1.11.1.8] an enzyme of the oxidoreductase class that catalyzes a series of reactions occurring in the synthesis of thyroxine; it catalyzes the oxidation of iodide to iodine, the iodination of tyrosyl residues of thyroglobulins, and the intramolecular condensation of such iodinated residues to form iodothyronines. Deficiency of the enzyme, an autosomal recessive disorder, results in congenital goiter. Called also thyroid peroxidase and thyroperoxidase.

Medical dictionary. 2011.

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  • Iodide — An iodide ion is an iodine atom with a −1 charge [Greenwood Earnshaw] . Compounds with iodine in formal oxidation state −1 are called iodides. This can include ionic compounds such as caesium iodide or covalent compounds such as phosphorus… …   Wikipedia

  • Iodide — The chemical form to which iodine in the diet is reduced before it is absorbed through the intestinal wall into the bloodstream and carried through the blood to the thyroid gland. * * * 1. The negative ion of iodine, I−. 2. Any salt of hydroiodic …   Medical dictionary

  • thyroid peroxidase — thy·roid per·ox·i·dase (thiґroid pər okґsĭ dās) iodide peroxidase …   Medical dictionary

  • Thyroid peroxidase — protein Name = thyroid peroxidase caption = width = HGNCid = 12015 Symbol = TPO AltSymbols = EntrezGene = 7173 OMIM = 606765 RefSeq = NM 175722 UniProt = P07202 PDB = ECnumber = 1.11.1.8 Chromosome = 2 Arm = Band = LocusSupplementaryData = pter… …   Wikipedia

  • hormone — hormonal, hormonic /hawr mon ik, moh nik/, adj. /hawr mohn/, n. 1. Biochem. any of various internally secreted compounds, as insulin or thyroxine, formed in endocrine glands, that affect the functions of specifically receptive organs or tissues… …   Universalium

  • List of EC numbers (EC 1) — This list contains a list of EC numbers for the first group, EC 1, oxidoreducatases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 1.1 Acting on the CH OH …   Wikipedia

  • Deiodinase — (or iodide peroxidase or Monodeiodinase ) is a peroxidase enzyme that is involved in the activation or deactivation of thyroid hormones. In general, T4 (thyroxine) is converted into T3 (triiodothyronine) by the deiodinase enzyme in target cells.… …   Wikipedia

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  • deiodinase — noun Iodide peroxidase, an enzyme …   Wiktionary

  • iodinase — SYN: iodide peroxidase …   Medical dictionary

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