17α-hydroxyprogesterone

17α-hydroxyprogesterone
A steroid hormone with medical use similar to that of progesterone. The acetate is an orally effective derivative, useful in conditions in which parenterally administered progesterone or the caproate is indicated; it possesses some androgenic potency and may cause virilizing changes in a female fetus. The caproate or hexanoate has essentially the same actions and uses as progesterone, but is more potent and has a longer duration of action. A precursor of the androgens, estrogens, and adrenocortical hormones.

Medical dictionary. 2011.

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  • 17α-hydroxyprogesterone aldolase — 17α hy·droxy·pro·ges·ter·one al·do·lase (hi drok″se pro jesґtə rōn alґdo lās) [EC 4.1.2.30] an enzyme of the lyase class that catalyzes the cleavage of the bond between carbons 17 and 20 in 17α hydroxyprogesterone… …   Medical dictionary

  • 17α-Hydroxyprogesteron — Strukturformel Allgemeines Freiname Hydroxyprogesteron …   Deutsch Wikipedia

  • hydroxyprogesterone — hy·droxy·pro·ges·ter·one hī .dräk sē prō jes tə .rōn or 17à hydroxyprogesterone .sev ən ten al fə n a synthetic derivative of progesterone used esp. in the form of its caproate C27H40O4 in progestational therapy (as for amenorrhea and abnormal… …   Medical dictionary

  • 17-Hydroxyprogesterone caproate — Systematic (IUPAC) name [(8R,9S,10R,13S,14S,17R) 17 acetyl 10,13 dimethyl 3 oxo 2,6,7,8,9,11,12,14,15,16 decahydro 1H cyclopenta[a]phenanthren 17 yl] hexanoate …   Wikipedia

  • steroid 17α-monooxygenase — ster·oid 17α mono·oxy·gen·ase (sterґoid mon″o okґsə jən ās) [EC 1.14.99.9] an enzyme of the oxidoreductase class that catalyzes the hydroxylation of steroids at the 17 position. The enzyme is a microsomal cytochrome P… …   Medical dictionary

  • 17-Hydroxyprogesterone — drugbox IUPAC name = 17 Hydroxypregn 4 ene 3,20 dione CAS number = ATC prefix = ATC suffix = PubChem = DrugBank = C=21 | H=30 | O=3 molecular weight = 330.22 melting point = 219 220 bioavailability = protein bound = metabolism = Liver elimination …   Wikipedia

  • 1720-desmolase — 17α hydroxyprogesterone aldolase …   Medical dictionary

  • 1720-lyase — 17α hydroxyprogesterone aldolase …   Medical dictionary

  • Progestin-induced virilisation — Maternal use of androgens or high doses of certain weakly androgenic synthetic progestogens (progestins) structurally related to testosterone can masculinize (virilize) the external genitalia of a female fetus during susceptible times in… …   Wikipedia

  • Progestin — Co inventor Luis E. Miramontes s signed laboratory notebook. October 15, 1951 A progestin is a synthetic[1] progestogen that has progestinic effects similar to progesterone. [2] …   Wikipedia

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