glycogen synthase

glycogen synthase
gly·co·gen syn·thase (gliґko-jən sinґthās) an enzyme of the transferase class that catalyzes the synthesis of glycogen by forming an α-1,4-glucoside linkage between the terminal hydroxyl group of glycogen chain and a glucosyl group donated by UDP-glucose. The reaction is highly regulated by allosteric effectors, by kinases and phosphatases, and by insulin. There are liver and muscle isoforms, each encoded by a separate gene; deficiency of either isoform, particularly the former, causes glycogen storage disease, type 0. In official nomenclature, called glycogen (starch) synthase.

Medical dictionary. 2011.

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  • Glycogen synthase — protein Name=glycogen synthase 1 (muscle) caption= width= HGNCid=4706 Symbol=GYS1 AltSymbols=GYS EntrezGene=2997 OMIM=138570 RefSeq=NM 002103 UniProt=P13807 PDB= ECnumber=2.4.1.11 Chromosome=19 Arm=q Band=13.3 LocusSupplementaryData=protein… …   Wikipedia

  • (glycogen-synthase-D) phosphatase — In enzymology, a [glycogen synthase D] phosphatase (EC number|3.1.3.42) is an enzyme that catalyzes the chemical reaction: [glycogen synthase D] + H2O ightleftharpoons [glycogen synthase I] + phosphateThus, the two substrates of this enzyme are… …   Wikipedia

  • [glycogen-synthase-D] phosphatase — [gly·co·gen syn·thase D] phos·pha·tase (gliґko jən sinґthās fosґfə tās) [EC 3.1.3.42] an enzyme of the hydrolase class that catalyzes the cleavage of a phosphoryl group from (inactive) glycogen synthase b to form (active)… …   Medical dictionary

  • Glycogen-Synthase — Dextrinkette, die durch Glykogen Synthase verlängert wird Glykogen Synthase oder Stärke Synthase heißen diejenigen Enzyme, die Dextrinketten durch Anhängen eines weiteren Glucose Moleküls verlängern. Dies ist der vorletzte Schritt in der Synthese …   Deutsch Wikipedia

  • Glycogen — is a polysaccharide of glucose (Glc) which functions as the secondary short term energy storage in animal cells. It is made primarily by the liver and the muscles, but can also be made by the brain, uterus, and the vagina. [Anatomy and Physiology …   Wikipedia

  • Glycogen storage disease — Classification and external resources Glycogen ICD 10 E74.0 …   Wikipedia

  • Glycogen storage disease type V — Classification and external resources ICD 10 E74.0 ICD 9 271.0 …   Wikipedia

  • Glycogen storage disease type III — Classification and external resources Micrograph of glycogen storage disease with histologic features consistent with Cori disease. Liver biopsy. H E stain …   Wikipedia

  • Glycogen phosphorylase — Phosphorylase The crystal structure of the rabit muscle glycogen phosphorylase AMP complex. AMP allosteric site (yellow), phosporylated Ser14 (orange), glycogen binding site (blue), catalytic site (red).[1] …   Wikipedia

  • Glycogen debranching enzyme — Amylo alpha 1, 6 glucosidase, 4 alpha glucanotransferase Identifiers Symbols AGL; GDE External IDs …   Wikipedia

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