glutamate decarboxylase

glutamate decarboxylase: glu·ta·mate de·car·box·y·lase (glooґtə-māt de-kahr-bokґsə-lās) [EC 4.1.1.15] an enzyme of the lyase class that catalyzes the decarboxylation of glutamate to form γ-aminobutyrate (GABA). The enzyme is a pyridoxal phosphate protein, and the reaction occurs within the mitochondria in kidney, and outside the mitochondria in brain. Deficiency of the brain enzyme may be the cause of convulsions that begin in infancy and are responsive to pyridoxine therapy. Called also glutamic acid decarboxylase.

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Glutamate decarboxylase — protein Name = Glutamic acid decarboxylase 1 caption = width = HGNCid = 4092 Symbol = GAD1 AltSymbols = GLUTAMATE DECARBOXYLASE, BRAIN, 67 KD; GAD67 EntrezGene = 2571 OMIM = 605363 RefSeq = UniProt = Q99259 PDB = ECnumber = 4.1.1.15 Chromosome =… … Wikipedia
glutamate — A salt or ester of glutamic acid. g. acetyltransferase 1. an enzyme catalyzing transfer of an acetyl group from N2 acetylornithine to l g. forming l ornithine and N acetyl l g., an activator of the urea cycle; … Medical dictionary
Ornithine decarboxylase — Identifiers EC number 4.1.1.17 CAS number 9024 60 6 … Wikipedia
Ornithine decarboxylase antizyme — is a ornithine decarboxylase inhibitor. It was first characterized in 1981.[1] The genes include OAZ1, OAZ2, and OAZ3. References ^ … Wikipedia
Aromatic L-amino acid decarboxylase — Ribbon diagram of a domestic pig DOPA decarboxylase dimer.[1] … Wikipedia
Orotidine 5'-phosphate decarboxylase — E. coli OMP decarboxylase.[1] Identifiers EC number … Wikipedia
Malonyl-CoA decarboxylase — Identifiers EC number 4.1.1.9 CAS number 9024 99 1 … Wikipedia
Pyrophosphomevalonate decarboxylase — mevalonate (diphospho) decarboxylase Identifiers Symbol MVD Entrez 4597 HUGO … Wikipedia
Oxaloacetate decarboxylase — Identifiers EC number 4.1.1.3 CAS number 9024 98 0 … Wikipedia
aspartate 1-decarboxylase — SYN: glutamate decarboxylase … Medical dictionary

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