- Gell and Coombs classification
- (jelґ k
mzґ) [Philip George Howthern Gell, British immunologist, 1914–2001; Robert Royston Amos Coombs, British immunologist, 1921–2006] see under classification.
Medical dictionary. 2011.
Gell and Coombs classification
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Gell and Coombs classification — a classification of immune mechanisms of tissue injury, called by Gell and Coombs “allergic reactions,†comprising four types: type I, immediate hypersensitivity reactions, mediated by IgE antibody; type II, antibody mediated hypersensitivity … Medical dictionary
classification — A systematic arrangement into classes or groups based on perceived common characteristics; a means of giving order to a group of disconnected facts. adansonian c. the c. of organisms based on giving equal weight to every character of the… … Medical dictionary
Robin Coombs — Robert Royston Amos ( Robin ) Coombs, (January 9 1921 ndash; February 25 2006), was a British immunologist, co discoverer of the Coombs test (1945) used for detecting antibodies in various clinical scenarios, such as Rh disease and blood… … Wikipedia
Immune response — Any reaction by the immune system. * * * immune response n a bodily response to an antigen that occurs when lymphocytes identify the antigenic molecule as foreign and induce the formation of antibodies and lymphocytes capable of reacting with it… … Medical dictionary
Arthus reaction — Ar·thus reaction är thəs , ȧr tues n a reaction that follows injection of an antigen into an animal in which hypersensitivity has been previously established and that involves infiltrations, edema, sterile abscesses, and in severe cases gangrene … Medical dictionary
serum sickness — n an allergic reaction to the injection of foreign serum manifested by hives, swelling, eruption, arthritis, and fever called also serum disease * * * a reaction that sometimes occurs 7 12 days after injection of a quantity of foreign antigen and … Medical dictionary
hypersensitivity — Abnormal sensitivity, a condition in which there is an exaggerated response by the body to the stimulus of a foreign agent. See allergy. contact h. 1. SYN: contact dermatitis. 2. SYN: delayed reaction. delayed h. 1 … Medical dictionary
delayed hypersensitivity reaction — a reaction of cell mediated immunity, named in contrast to immediate hypersensitivity reactions because its onset is 24 to 72 hours after the antigenic challenge; the term is usually used to denote the subset of type IV hypersensitivity reactions … Medical dictionary
hypersensitivity reaction — a reaction in which the body mounts an exaggerated or inappropriate immune response to a substance either foreign or perceived as foreign, resulting in local or general tissue damage. Such reactions are usually classified as types I–IV on the… … Medical dictionary
Hypersensitivity — NOTOC Infobox Disease Name = PAGENAME Caption = DiseasesDB = 28827 ICD10 = ICD10|T|78|4|t|66 ICD9 = ICD9|995.3 ICDO = OMIM = MedlinePlus = eMedicineSubj = eMedicineTopic = MeshID = D006967 Hypersensitivity (also called hypersensitivity reaction)… … Wikipedia
