ganglioside GM2

ganglioside GM2
a ganglioside containing an N-acetylgalactosamine residue linked to the galactose of the core structure; it accumulates abnormally in tissues in GM2 gangliosidoses.

Medical dictionary. 2011.

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  • Ganglioside GM2 activator protein — is (GM2 AP) is a lipid transfer protein that stimulates the enzymatic processing of gangliosides, and also T cell activation through lipid presentation.This protein binds molecules of ganglioside GM2, extracts them from membranes, and presents… …   Wikipedia

  • GM2 (ganglioside) — GM2 is a type of ganglioside.It is associated with GM2 gangliosidoses (for example, Tay Sachs disease.)cite journal |author=Guetta E, Peleg L |title=Rapid detection of fetal mendalian disorders: tay sachs disease |journal=Methods Mol. Biol.… …   Wikipedia

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  • ganglioside GM1 — a ganglioside structurally similar to ganglioside GM2 but with an additional galactose residue linked to the N acetylgalactosamine residue of GM2; it accumulates abnormally in tissues in GM1 gangliosidoses …   Medical dictionary

  • GM2 gangliosidosis — any of a group of lysosomal storage diseases characterized by abnormal accumulation of ganglioside GM2 and related glycoconjugates, due to deficiency of activity of one or more hexosaminidase isozymes or of an activator protein necessary for… …   Medical dictionary

  • Ganglioside — is a molecule composed of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acids (e.g. n acetylneuraminic acid, NANA) linked on the sugar chain. The 60+ known gangliosides differ mainly in the position and number of NANA …   Wikipedia

  • GM2-Aktivator — Bändermodell nach PDB  …   Deutsch Wikipedia

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  • GM2-gangliosidosis, AB variant — Infobox Disease Name = PAGENAME Caption = DiseasesDB = 32644 ICD10 = ICD9 = ICDO = OMIM = 272750 MedlinePlus = eMedicineSubj = ped eMedicineTopic = 3016 MeshID = D049290 GM2 gangliosidosis, AB variant is a rare, autosomal recessive metabolic… …   Wikipedia

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