- ganglioside GM1
- a ganglioside structurally similar to ganglioside GM2 but with an additional galactose residue linked to the N-acetylgalactosamine residue of GM2; it accumulates abnormally in tissues in GM1 gangliosidoses.
Medical dictionary. 2011.
ganglioside GM1
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Ganglioside — is a molecule composed of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acids (e.g. n acetylneuraminic acid, NANA) linked on the sugar chain. The 60+ known gangliosides differ mainly in the position and number of NANA … Wikipedia
GM1 — This article is about the neural compound. For the engine boosting compound, see GM 1. GM1 IUPAC name … Wikipedia
GM1 gangliosidosis — A genetic lipid storage disorder that is similar in certain respects to Hurler syndrome and Tay Sachs disease but which affects both the brain and the viscera (the internal organs). GM1 gangliosidosis causes skeletal deformities and exerts severe … Medical dictionary
Ganglioside GM2 activator protein — is (GM2 AP) is a lipid transfer protein that stimulates the enzymatic processing of gangliosides, and also T cell activation through lipid presentation.This protein binds molecules of ganglioside GM2, extracts them from membranes, and presents… … Wikipedia
Ganglioside — Struktur des GM1 Gangliosids Ganglioside [1][2][3][4] … Deutsch Wikipedia
Ganglioside galactosyltransferase — In enzymology, a ganglioside galactosyltransferase (EC number|2.4.1.62) is an enzyme that catalyzes the chemical reaction:UDP galactose + N acetyl D galactosaminyl (N acetylneuraminyl) D galactosyl 1,4 beta D glucosyl N acylsphingosine… … Wikipedia
ganglioside — A glycosphingolipid chemically similar to cerebrosides but containing one or more sialic (N acetylneuraminic or N glycolylneuraminic) acid residues; found principally in nerve tissue, spleen, and thymus; GM1 accumulates in generalized… … Medical dictionary
Anti-ganglioside antibodies — AutoAbBox Autoantigen = ganglioside OneIsoform = CommentOneIsoform Answer only if true OneGene = OneOrgan = OneTissue = OneCell = OneAlso = OneDisease = OneIgClass = OneIgGSubclass = OneHLA1 = OneHLA2 = OneHLA3 = OneTCellRestr = SharedInfo = Yes… … Wikipedia
gangliosidosis — Any disease characterized, in part, by the abnormal accumulation within the nervous system of specific gangliosides, e.g., GM2 g., Tay Sachs disease, caused by hexosaminidase A enzyme deficiency with accumulation of GM2 ganglioside. SYN … Medical dictionary
hexosaminidase — General term for enzymes cleaving N acetylhexose ( e.g., N acetylglucosamine) residues from gangliosidelike oligosaccharides. At least four specific enzymes carrying out this type of reaction are known: α N acetyl d galactosaminidase, α N acetyl… … Medical dictionary
