formyltetrahydrofolate dehydrogenase

formyltetrahydrofolate dehydrogenase
for·myl·tet·ra·hy·dro·fo·late de·hy·dro·gen·ase (form″əl-tet″rə-hi″dro-foґlāt de-hiґdro-jən-ās) [EC 1.5.1.6] an enzyme of the oxidoreductase class that catalyzes the oxidative decarboxylation of 10-formyltetrahydrofolate to produce tetrahydrofolate, using NADP+as an electron acceptor. The reaction occurs in liver to release excess active one-carbon fragments and maintain sufficient tetrahydrofolate for metabolism.

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