fil·a·min (filґə-min) a family of actin-binding proteins (in mammals, filamins A, B, and C) that cross-link actin filaments to form a network in the cortex of many cells and regulate changes in cellular shape and motility; they also play a role in second messenger signaling.

Medical dictionary. 2011.

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  • Filamin — Filamine (FLN) sind Proteine bei Eukaryoten und gehören zu den Aktin bindenden Proteinen (ABP). Sie sind an der Quervernetzung von Aktinfilamenten, einem Hauptbestandteil des Zytoskeletts, sowie der Vernetzung von Aktinfilamenten mit Proteinen in …   Deutsch Wikipedia

  • filamin — A protein that binds to F actin, cross linking it to form an isotropic network; the binding does not require Ca2+. It was originally isolated from smooth muscle and is a homodimer 2 x 250 kD. Similar to actin binding protein (ABP) from leucocytes …   Dictionary of molecular biology

  • filamin — noun Any of a class of proteins that bind actin filaments and anchor membrane proteins …   Wiktionary

  • filamen, filamin — A high molecular weight, actin binding protein that is part of the intracellular filamentous structure of fibroblastic cells; its distribution in cells is derived from its interaction with polymerized actin …   Medical dictionary

  • FLNC (gene) — Filamin C, gamma (actin binding protein 280), also known as FLNC, is a human gene.cite web | title = Entrez Gene: FLNC filamin C, gamma (actin binding protein 280)| url = Cmd=ShowDetailView… …   Wikipedia

  • FLNB — Filamin B, beta (actin binding protein 278), also known as FLNB, is a human cytoplasmic protein.cite web | title = Entrez Gene: FLNB filamin B, beta (actin binding protein 278)| url =… …   Wikipedia

  • FBLIM1 — Filamin binding LIM protein 1, also known as FBLIM1, is a human gene.cite web | title = Entrez Gene: FBLIM1 filamin binding LIM protein 1| url = Cmd=ShowDetailView TermToSearch=54751| accessdate =… …   Wikipedia

  • FLNA — Filamin A, alpha (actin binding protein 280), also known as FLNA, is a human gene. PBB Summary section title = summary text = Actin binding protein, or filamin, is a 280 kD protein that crosslinks actin filaments into orthogonal networks in… …   Wikipedia

  • FILIP1 — Filamin A interacting protein 1, also known as FILIP1, is a human gene.cite web | title = Entrez Gene: FILIP1 filamin A interacting protein 1| url = Cmd=ShowDetailView TermToSearch=27145|… …   Wikipedia

  • Myotilin — Rendering based on PDB 2KDG …   Wikipedia

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