insulinlike growth factors

insulinlike growth factors: (IGF) serum peptides with insulin-like actions, formerly called somatomedins (q.v.). IGF-I (formerly somatomedin C) is an important growth hormoneâ€“dependent mediator of cell growth and replication. IGF-II (formerly somatomedin A) appears to be essential for normal embryonic development and may play special roles in the central nervous system. Both are similar in sequence and structure to proinsulin.

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nonsuppressible insulinlike activity — (NSILA) insulin like growth factors … Medical dictionary
activity — 1. In electroencephalography, the presence of neurogenic electrical energy. 2. In physical chemistry, an ideal concentration for which the law of mass action will apply perfectly; the ratio of the a. to the true concentr … Medical dictionary
somatomedin — S. A is a peptide (MW about 4,000), synthesized in the liver and probably in the kidney, that is capable of stimulating certain anabolic processes in bone and cartilage, such as synthesis of DNA, RNA, and protein (including chondromucoprotein),… … Medical dictionary
factor — 1. One of the contributing causes in any action. 2. One of the components that by multiplication makes up a number or expression. 3. SYN: gene. 4. A vitamin or other essential element. 5. An event, characteristic, or other definable entity that … Medical dictionary

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