insulinlike growth factors
- insulinlike growth factors
- (IGF) serum peptides with insulin-like actions, formerly called somatomedins (q.v.). IGF-I (formerly somatomedin C) is an important growth hormoneâ€“dependent mediator of cell growth and replication. IGF-II (formerly somatomedin A) appears to be essential for normal embryonic development and may play special roles in the central nervous system. Both are similar in sequence and structure to proinsulin.
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