segmental demyelination

segmental demyelination
degeneration of the myelin sheath in segments between successive nodes of Ranvier, with preservation of the axon; seen in a variety of polyneuropathic conditions.

Cross-section of sural nerve in chronic inflammatory demyelination polyradiculoneuropathy. (A), Segmental demyelination; (B), relatively unaffected area.


Medical dictionary. 2011.

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