Medical dictionary. 2011.
Mutation, acquired — A change in a gene or chromosome that occurs in a single cell after the conception of the individual. That change is then transmitted to all cells descended from that cell, giving rise to a clone of cells marked by the mutation. Acquired… … Medical dictionary
Mutation — A permanent change, a structural alteration, in the DNA or RNA. In humans and many other organisms, mutations occur in DNA. However, in retroviruses like HIV, mutations occur in RNA which is the genetic material of retroviruses. In most cases,… … Medical dictionary
Acquired — Anything that is not present at birth but develops some time later. In medicine, the word acquired implies new or added. An acquired condition is new in the sense that it is not genetic (inherited) and added in the sense that was not present at… … Medical dictionary
Mutation — For other uses, see Mutation (disambiguation). Part of the Biology series on Evolution … Wikipedia
Mutation, germline — A heritable change in the DNA that occurred in a germ cell (a cell destined to become an egg or in the sperm) or the zygote (the conceptus) at the single cell stage. When transmitted to a child, a germline mutation is incorporated in every cell… … Medical dictionary
Mutation, somatic — A change in a gene or chromosome that occurs in a general body cell, as opposed to a germ cell, and so cannot be transmitted to children. A somatic mutation occurs in a single cell after the conception of the individual. That change is then… … Medical dictionary
JAK2-Mutation — Die JAK2 V617F Punktmutation ist eine genetische Mutation, die ein wichtiger neuer Marker für die Diagnose der chronische myeloproliferative Erkrankungen oder myeloproliferative Syndrome (häufig MPS abgekürzt) ist, einer Gruppe von Krankheiten,… … Deutsch Wikipedia
Adaptive mutation — Evolutionary theory describes that mutagenesis occurs randomly, regardless of the utility of a genetic mutation to the organism. If it is beneficial or neutral, the organism will survive to reproduce and pass on the mutation. However, molecular… … Wikipedia
Germline mutation — A germline mutation is any detectable and heritable variation in the lineage of germ cells. Mutations in these cells are transmitted to offspring, while, on the other hand, those in somatic cells are not. A germline mutation gives rise to a… … Wikipedia
Somatic mutation — A change in a gene or chromosome that occurs in a general body cell, as opposed to a germ cell, and so cannot be transmitted to children. A somatic mutation occurs in a single cell after the conception of the individual. That change is then… … Medical dictionary
