class II antigens

class II antigens
major histocompatibility antigens found only on immunocompetent cells, primarily B lymphocytes and macrophages; they are found on molecules consisting of two noncovalently bound chains, the 34,000-dalton α chain and 29,000-dalton β chain, both glycoproteins partially embedded in the cell membrane and both determined by MHC genes. The human HLA-D, -DR, -DP, and -DQ loci are all associated with antigenic determinants on class II antigen molecules.

Medical dictionary. 2011.

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