- cytotoxic antibody
- any specific antibody directed against cellular antigens, which when bound to the antigen, activates the complement pathway or activates killer cells, resulting in cell lysis.
Medical dictionary. 2011.
cytotoxic antibody
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Antibody-dependent cell-mediated cytotoxicity — (ADCC) is a mechanism of cell mediated immunity whereby an effector cell of the immune system actively lyses a target cell that has been bound by specific antibodies. It is one of the mechanisms through which antibodies, as part of the humoral… … Wikipedia
Cytotoxic T cell — Antigen presentation stimulates T cells to become either cytotoxic CD8+ cells or helper CD4+ cells. A cytotoxic T cell (also known as TC, Cytotoxic T Lymphocyte, CTL, T Killer cell, cytolytic T cell, CD8+ T cells or killer T cell) belongs to a… … Wikipedia
Antibody — Immunoglobulin redirects here. For the immunoglobulin family, see Immunoglobulin superfamily. Antibodies redirects here. For the film, see Antibodies (film). Each antibody binds to a specific antigen; an interaction similar to a lock and key. An… … Wikipedia
antibody-mediated cytotoxic hypersensitivity — type II h … Medical dictionary
antibody-mediated cytotoxic hypersensitivity reaction — type II hypersensitivity r … Medical dictionary
Monoclonal antibody therapy — Each antibody binds only one specific antigen. Monoclonal antibody therapy is the use of monoclonal antibodies (or mAb) to specifically bind to target cells or proteins. This may then stimulate the patient s immune system to attack those cells.… … Wikipedia
monoclonal antibody — Biotech. antibody produced by a laboratory grown cell clone, either of a hybridoma or a virus transformed lymphocyte, that is more abundant and uniform than natural antibody and is able to bind specifically to a single site on almost any chosen… … Universalium
Bispecific antibody — A bispecific antibody is a monoclonal antibodies which is designed to bind to two different antigens.One benefit of this approach is that it is possible for such an antibody to simultaneously bind to a cytotoxic cell (using a receptor like CD3)… … Wikipedia
cytotoxicity — The quality or state of being cytotoxic. antibody dependent cell mediated c. (ADCC) a form of cell mediated c. that functions by binding of the FC region of IgG antibodies to Fc receptors on leukocytes. The FAB region of the antibody binds to the … Medical dictionary
spermatoxin — A cytotoxic antibody specific for spermatozoa. SYN: spermotoxin. * * * sper·ma·tox·in spər mə .täk sən n a substance (as an antibody) poisonous to spermatozoa or derived from spermatozoa and tending to prevent conception * * * sper·ma·tox·in… … Medical dictionary
