5-aminolevulinate synthase

5-aminolevulinate synthase
5-ami·no·lev·u·lin·ate syn·thase (ə-me″no-lev″u-linґāt sinґthās) [EC 2.3.1.37] an enzyme of the transferase class that catalyzes the condensation of the succinyl group from succinyl coenzyme A with glycine to form δ-aminolevulinate. It is a pyridoxal phosphate protein and the reaction occurs in mitochondria as the first step of the heme biosynthetic pathway. The enzyme is a key regulatory enzyme in heme biosynthesis and, in liver at least, is feedback inhibited by heme. Abbreviated ALAS. Written also δ-aminolevulinate synthase.

Medical dictionary. 2011.

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  • δ-aminolevulinate synthase — δ aminolevulinate synthase. См. δ аминолевулинатсинтаза. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • aminolevulinate dehydratase — ami·no·lev·u·lin·ate de·hy·dra·tase (ə me″no lev″u linґāt de hiґdrə tās) porphobilinogen synthase …   Medical dictionary

  • Methyl aminolevulinate — Systematic (IUPAC) name methyl 5 amino 4 oxo pentanoate Clinical data AHFS/Drugs.com …   Wikipedia

  • Aminolevulinic acid synthase — protein Name = aminolevulinate, delta , synthase 1 caption = width = HGNCid = 396 Symbol = ALAS1 AltSymbols = ALAS3, ALAS EntrezGene = 211 OMIM = 125290 RefSeq = NM 000688 UniProt = P13196 PDB = ECnumber = 2.3.1.37 Chromosome = 3 Arm = p Band =… …   Wikipedia

  • Porphobilinogen synthase — Identifiers EC number 4.2.1.24 CAS number 9036 37 7 …   Wikipedia

  • porphobilinogen synthase — por·pho·bi·lin·o·gen syn·thase (por″fo bĭ linґo jən sinґthās) [EC 4.2.1.24] an enzyme of the lyase class that catalyzes the condensation of two molecules of δ aminolevulinate to form porphobilinogen in the synthesis of… …   Medical dictionary

  • δ-aminolevulinate dehydratase — SYN: porphobilinogen synthase …   Medical dictionary

  • ALAS — • delta aminolevulinate synthase …   Dictionary of medical acronyms & abbreviations

  • List of EC numbers (EC 2) — This list contains a list of EC numbers for the second group, EC 2, transferases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 2.1: Transferring One… …   Wikipedia

  • Mitochondrion — For the metal band, see Mitochondrion (band). Two mitochondria from mammalian lung tissue displaying their matrix and membranes as shown by electron microscopy …   Wikipedia

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