β-aminoisobutyrate–pyruvate transaminase

β-ami·no·iso·bu·ty·rate–py·ru·vate trans·am·i·nase (ə-me″no-i″so-buґtər-āt piґroo-vāt trans-amґĭ-nās) an enzyme of the transferase class that catalyzes the oxidative deamination of R-β-aminoisobutyrate, transferring the amino group to pyruvate; the reaction is a step in the catabolism of thymine. Deficiency of the enzyme, an autosomal recessive trait, causes β-aminoisobutyricaciduria. In EC nomenclature, called (R)-3-amino-2-methylpropionate–pyruvate transaminase. Called also β-aminoisobutyrate–pyruvate aminotransferase.