conditionally replicative adenovirus

conditionally replicative adenovirus
mutant adenoviruses that can replicate only inside certain types of tumor cells, infecting those cells with lethal abnormalities and thus being potentially useful in gene therapy for cancer.

Medical dictionary. 2011.

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  • Oncolytic virus — An oncolytic virus is a virus that preferentially infects and lyses cancer cells; these have obvious functions for cancer therapy, both by direct destruction of the tumour cells, and, if modified, as vectors enabling genes expressing anticancer… …   Wikipedia

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