short-chain acyl-CoA dehydrogenase (SCAD) deficiency

short-chain acyl-CoA dehydrogenase (SCAD) deficiency
a defect in mitochondrial beta oxidation due to a mutation in the gene (locus: 12q22-qter) encoding the acyl-CoA dehydrogenase that acts on short chain length fatty acids. Clinical presentation is variable, but myopathy and abnormalities of carnitine accumulation and excretion are often present.

Medical dictionary. 2011.

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