N-acetylglutamic acid

N-acetylglutamic acid
N-ac·e·tyl·glu·tam·ic ac·id (as″ə-təl-) (as″ə-tēl″gloo-tamґik) glutamic acid acetylated at its N-terminus, a necessary cofactor in the synthesis of carbamoyl phosphate catalyzed by carbamoyl-phosphate synthase (ammonia). The molecule is an allosteric activator of this enzyme and hence a positive regulator of ureagenesis.

Medical dictionary. 2011.

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  • N-acetylglutamate — The salt of N acetylglutamic acid. An activator of carbamoyl phosphate synthetase I during urea synthesis; this amino acid causes a configurational change in the enzyme, increasing the activity of that enzyme …   Medical dictionary

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