acetyl-CoA C-acetyltransferase

acetyl-CoA C-acetyltransferase
ac·e·tyl-CoA C-ac·e·tyl·trans·fer·ase (asґə-təl-ko-aґ as″ə-təl-transґfər-ās) (as″ə-tēlґko-aґ as″ə-tēl-transґfər-ās) [EC 2.3.1.9] an enzyme of the transferase class that catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A; it can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation. A mitochondrial form is involved in ketone body synthesis, and a cytoplasmic form is involved in the synthesis of cholesterol and other isoprenoids.

Medical dictionary. 2011.

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