triple marker test

triple marker test
a blood test used in the prenatal diagnosis of Down's syndrome, which can be performed at about the 16th week of pregnancy. Levels of alpha-fetoprotein (afp), unconjugated oestriol (uE3), and human chorionic gonadotrophin in the serum are computed with maternal age to determine the statistical likelihood of the fetus being affected. If the risk is high, the diagnosis can be confirmed by chromosome analysis.

Medical dictionary. 2011.

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  • Triple test — The triple test, also called triple screen, the Kettering test or the Bart s test, is an investigation performed during pregnancy in the second trimester to classify a patient as either high risk or low risk for chromosomal abnormalities (and… …   Wikipedia

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  • ТЕСТ ТРОЙНОГО МАРКЕРА — (triple marker test) анализ крови, выполняющийся приблизительно на 16 ой неделе беременности для пренатальной диагностики синдрома Дауна. При этом определяются уровни альфа фетопротеина, (АФП), несвязанного эстриола и человеческого хорионического …   Толковый словарь по медицине

  • human chorionic gonadotrophin — (HCG) a hormone, similar to the pituitary gonadotrophin that is produced by the placenta during pregnancy. Large amounts are excreted in the urine, and this is used as the basis for most pregnancy test. The level of HCG in the serum is one of the …   Medical dictionary

  • Down's syndrome — a condition resulting from a genetic abnormality in which an extra chromosome is present (there are three no. 21 chromosomes instead of the usual two), giving a total of 47 chromosomes rather than the normal 46. The chances of having a Down s… …   Medical dictionary

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  • Human chorionic gonadotropin — chorionic gonadotropin, alpha polypeptide Identifiers Symbol CGA Alt. symbols FSHA, GPHa, GPHA1, HCG, LHA, TSHA …   Wikipedia

  • Alpha-fetoprotein — (AFP) is a molecule produced in the developing embryo and fetus. In humans, AFP levels decrease gradually after birth, reaching adult levels by 8 to 12 months. Normal adult AFP levels are low, but detectable; however, AFP has no known function in …   Wikipedia

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