Taxane — sind natürlich vorkommende Zytostatika, also Stoffe, die das Zellwachstum bzw. die Zellteilung hemmen. Chemisch gesehen gehören Taxane zu den Diterpenoiden (Diterpene). Seit Anfang der 1990er Jahre werden Taxane in der Krebstherapie eingesetzt.… … Deutsch Wikipedia
Taxane — [zu lateinisch taxus »Eibe«] die, von verschiedenen Eibenarten gebildete Gruppe von Naturstoffen, die als Mitosehemmer zur Tumorbehandlung eingesetzt werden. Die therapeutisch zuerst verwendete Substanz war das in der pazifischen Eibe (Taxus… … Universal-Lexikon
Taxane — Les taxanes sont une classe très utilisée d agents chimiothérapeutiques[1],[2]. Cette classe comprend le paclitaxel (Taxol) et le docétaxel (Taxotère). À l origine, le paclitaxel (Taxol) a été isolé de l if de l ouest (Taxus brevifolia)[1], un if … Wikipédia en Français
Taxane — The taxanes are diterpenes produced by the plants of the genus Taxus (yews). As their name suggests, they were first derived from natural sources, but some have been synthesized artificially. Taxanes include paclitaxel and docetaxel. Paclitaxel… … Wikipedia
taxane — A type of drug that blocks cell growth by stopping mitosis (cell division). Taxanes interfere with microtubules (cellular structures that help move chromosomes during mitosis). They are used to treat cancer. A taxane is a type of mitotic… … English dictionary of cancer terms
Taxane 10beta-hydroxylase — In enzymology, a taxane 10beta hydroxylase (EC number|1.14.13.76) is an enzyme that catalyzes the chemical reaction:taxa 4(20),11 dien 5alpha yl acetate + NADPH + H+ + O2 ightleftharpoons 10beta hydroxytaxa 4(20),11 dien 5alpha yl acetate + NADP+ … Wikipedia
Taxane 13alpha-hydroxylase — In enzymology, a taxane 13alpha hydroxylase (EC number|1.14.13.77) is an enzyme that catalyzes the chemical reaction:taxa 4(20),11 dien 5alpha ol + NADPH + H+ + O2 ightleftharpoons taxa 4(20),11 dien 5alpha,13alpha diol + NADP+ + H2OThe 4… … Wikipedia
taxane — noun any of a class of diterpenoid drugs that inhibit cancer cell growth and division. Examples are Paclitaxel (taxol) and Docetaxel (taxotere) … Wiktionary
taxane — n. any of a group of cytotoxic drugs formerly extracted from a species of yew tree (Taxus) but now synthesized or produced by biotechnological methods. These drugs interact with tubulin, a protein involved in cell division, and have been found to … The new mediacal dictionary
taxane — n.f. Substance antitumorale … Le dictionnaire des mots absents des autres dictionnaires
