a monoclonal antibody used to treat severe cases of Crohn's disease and rheumatoid arthritis that have failed to respond to treatment with corticosteroids or immunosuppressants and antirheumatic drugs, respectively. It acts as an immunosuppressant by inhibiting the tumour necrosis factor TNF-a. It is administered by infusion. Trade name: Remicade.

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in·flix·i·mab (in-flikґsĭ-mab) a chimeric human-murine immunoglobulin that acts as an anti–tumor necrosis factor antibody; administered intravenously in treatment of Crohn disease and rheumatoid arthritis.

Medical dictionary. 2011.

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