bile-acid sequestrant

bile-acid sequestrant
a drug that binds to bile acids, forming a complex that is excreted in the faeces. Bile acids are formed in the liver from cholesterol and the effect of loss of bile acids is a reduction in total body cholesterol and a decrease in low-density lipoprotein serum levels. These drugs, which include colestyramine and colestipol, are used to treat patients with abnormally high blood cholesterol levels who are liable to develop coronary heart disease.

Medical dictionary. 2011.

Игры ⚽ Поможем решить контрольную работу

Look at other dictionaries:

  • Bile acid sequestrant — The bile acid sequestrants are a group of medications used for binding certain components of bile in the gastrointestinal tract. They disrupt the enterohepatic circulation of bile acids by sequestering them and preventing their reabsorption from… …   Wikipedia

  • bile-acid sequestrant — a drug that binds to bile acids, forming a complex that is excreted in the faeces. Bile acids are formed in the liver from cholesterol and the effect of loss of bile acids is a reduction in total body cholesterol and a decrease in low density… …   The new mediacal dictionary

  • Bile acid — Bile acids (also known as bile salts) are steroid acids found predominantly in the bile of mammals. In humans taurocholic acid, and glycocholic acid (derivatives of cholic acid) represent approximately eighty percent of all bile acids. The two… …   Wikipedia

  • Bile — or gall is a bitter yellow or green alkaline fluid secreted by hepatocytes from the liver of most vertebrates. In many species, bile is stored in the gallbladder between meals and upon eating is discharged into the duodenum where the bile aids… …   Wikipedia

  • sequestrant — se·ques·trant trənt n a sequestering agent (as citric acid) * * * se·ques·trant (sə kwesґtrənt) a sequestering agent, as, for example, cholestyramine resin, which binds bile acids in the intestine, thus preventing their absorption …   Medical dictionary

  • Cholestyramine — Clinical data Trade names Questran AHFS/Drugs.com …   Wikipedia

  • Primary biliary cirrhosis — Classification and external resources Micrograph of primary biliary cirrhosis showing bile duct inflammation and injury. H E stain …   Wikipedia

  • Colesevelam — Clinical data Trade names Welchol AHFS/Drugs.com …   Wikipedia

  • Colestipol — Systematic (IUPAC) name Copolymer of N (2 aminoethyl) N [2 (2 aminoethylamino)ethyl]ethane 1,2 diamine and 2 (chloromethyl)oxirane Clinical data Trade names …   Wikipedia

  • Management of Crohn's disease — involves first treating the acute symptoms of the disease, then maintaining remission. Treatment initially involves the use of medications to eliminate infections, generally antibiotics, and reduce inflammation, generally aminosalicylate anti… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”